I'm honestly in it right now... I've got a huge personal project that I need to get over the line, and it's been extremely confusing and completely physically exhausting too, I haven't been able to keep up my exercises which means I haven't been able to manage my back and neck issues quite as well as I need to, so now pain and headaches creep into the equation. At the same time work has been intense, for at least 2 months and something really has to give... at least until I get this project completed in the next month.
Personally I think work is going to have to be the thing that gives, which is a shame because it is going to cause some havoc - but since it's never a good time to take time off, I guess that means that it's just as good a time as any to take off.